The various physiochemical properties affecting the drug action are- 1. Ionization 5. Protein bonding 2. Solubility 6. Chelation 3. Partition coefficient 7. Bioisosterism 4. Hydrogen bonding 8. Stereoisomerism Ionization: It is necessary to know whether a molecule will be ionized at a given pH simply by knowing if the functional groups on the … Read more
The biological membrane (or cell membrane and plasma membrane) is a selectively permeable membrane that allows only certain substances to pass through it and acts as a barrier between the inner and outer surfaces of the cell. Cell membrane comprises lipids and proteins along with other living molecules, which participate in the normal functioning of … Read more
Medicinal chemistry roots can be found in the fertile mix of ancient folk medicine and early natural product chemistry, hence its name. As appreciation for the links between chemical structure and observed biological activity grew, medicinal chemistry began to emerge about 150 years ago as a distinct discipline intending to explore these relationships via chemical … Read more
An agonist and an antagonist are two types of molecules that interact with receptors in the body, but they have opposite effects on the receptor and its downstream signaling pathways. Agonists: An agonist is a chemical that bind to a receptor and activates the receptor to produce a biological response. For example, Heroin, methadone, morphine … Read more
A receptor is a specialized protein molecule, typically found on the surface of a cell or within its interior, that is capable of binding to specific signaling molecules called ligands. Receptors play a crucial role in cellular communication and signal transduction, serving as molecular switches that initiate cellular responses to extracellular stimuli. Or Receptor is … Read more
Medicinal Chemistry is the branch of science that deals with the modification and synthesis of drug molecules. Or Medicinal chemistry is the chemistry discipline concerned with design, development and synthesis of pharmaceutical drugs. Medicinal chemistry lies at the intersection of chemistry, biology, and pharmacology, focusing on the design, synthesis, and development of pharmaceutical agents with … Read more
बोर्ड ऑफ टेक्निकल एजुकेशन, उत्तर प्रदेश, लखनऊ ने सम सेमेस्टर (जून 2024) और वार्षिक पद्दति के छात्रों के लिए वार्षिक पद्दति की परीक्षा का कार्यक्रम जारी कर दिया है। परीक्षाएं जुलाई 2024 में आयोजित की जाएंगी। परीक्षा कार्यक्रम परीक्षा से सम्बंधित कोई भी जानकारी प्राप्त करने के लिए दिए गए फॉर्म को भरिये महत्वपूर्ण निर्देश … Read more
Hey there, future doctors and medical whizzes! The National Board of Examinations in Medical Sciences (NBEMS) just released a sneak peek at the upcoming exam schedule for the rest of 2024. This way, you can plan your studying and ace those tests! Here’s a quick rundown of the important dates: Month Exam Name Date May … Read more
The Indian Pharmacopoeia Commission (IPC) is an autonomous institution under the Ministry of Health & Family Welfare, Government of India, responsible for setting standards for drugs in the country through the Indian Pharmacopoeia (IP). The 29th Skill Development Programme on Pharmacovigilance is an initiative by IPC aimed at enhancing skills and knowledge in the field … Read more
Dear Students, Congratulations on embarking on your journey of education and self-discovery! As you navigate the vast sea of knowledge, you must equip yourself with the right tools to sail smoothly. Books, with their unparalleled ability to transport us to different worlds, challenge our perspectives, and ignite our imaginations, stand as invaluable companions on this … Read more
