Med. Chem-I (Unit 1) Archives - Pharmacareerinsider

Bioisosterism

by punetkumar987April 20, 2024April 20, 20240

Bioisosters are substituents or groups with similar physical or chemical properties that produce broadly similar biological properties to other chemical compounds. The relation between bioisosteres …

Drug metabolism or Bio-transformation

by punetkumar987April 20, 2024April 20, 20240

Drug metabolism refers to the biochemical processes by which the body chemically modifies pharmaceutical compounds to make them more water-soluble and easier to eliminate from …

Stereoisomerism of drugs

by punetkumar987April 20, 2024April 20, 20240

Stereochemistry involves the study of the three-dimensional nature of molecules. It is the study of the chiral molecules. Conformational Isomers: Different arrangements of atoms that …

PHYSIOCHEMICAL PROPERTIES IN RELATION TO BIOLOGICAL ACTION

by punetkumar987April 20, 2024April 20, 20240

The various physiochemical properties affecting the drug action are- 1. Ionization 5. Protein bonding 2. Solubility 6. Chelation 3. Partition coefficient 7. Bioisosterism …

Structure of Biological Membrane

by punetkumar987April 20, 2024April 20, 20240

The biological membrane (or cell membrane and plasma membrane) is a selectively permeable membrane that allows only certain substances to pass through it and acts …

HISTORY AND DEVELOPMENT OF MEDICINAL CHEMISTRY

by punetkumar987April 20, 2024April 20, 20240

Medicinal chemistry roots can be found in the fertile mix of ancient folk medicine and early natural product chemistry, hence its name. As appreciation for …

Agonist and Antagonist

by punetkumar987April 19, 2024April 19, 20240

An agonist and an antagonist are two types of molecules that interact with receptors in the body, but they have opposite effects on the receptor …

What is receptor?

by punetkumar987April 19, 2024April 19, 20240

A receptor is a specialized protein molecule, typically found on the surface of a cell or within its interior, that is capable of binding to …

Introduction to Medicinal Chemistry

by punetkumar987April 19, 2024April 19, 20240

Medicinal Chemistry is the branch of science that deals with the modification and synthesis of drug molecules. Or Medicinal chemistry is the chemistry discipline concerned …