Effect of Substituent on Acidity of Phenol

Introduction: The acidity of phenol is influenced by the nature and position of substituents on the aromatic ring. Substituents can either enhance or diminish the acidity of phenol. Here’s a breakdown of the effect of substituents on the acidity of phenol: 1. Electron-Withdrawing Substituents (EWS): Effect: Substituents such as nitro (NO2), carbonyl (COR), and sulfonyl … Read more

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