Tag: physicochemical properties in relation to biological action

Apr 20

PHYSIOCHEMICAL PROPERTIES IN RELATION TO BIOLOGICAL ACTION

The various physiochemical properties affecting the drug action are- 1. Ionization                            5. Protein bonding 2. Solubility                            6. Chelation 3. Partition coefficient             7. Bioisosterism 4. Hydrogen bonding              8. Stereoisomerism Ionization: It is necessary to know whether a molecule will be ionized at a given pH simply by knowing if the functional groups on the […]

Apr 19

Introduction to Medicinal Chemistry

Medicinal Chemistry is the branch of science that deals with the modification and synthesis of drug molecules. Or Medicinal chemistry is the chemistry discipline concerned with design, development and synthesis of pharmaceutical drugs. Medicinal chemistry lies at the intersection of chemistry, biology, and pharmacology, focusing on the design, synthesis, and development of pharmaceutical agents with […]