physicochemical properties in relation to biological action slideshare

The various physiochemical properties affecting the drug action are- 1. Ionization                            5. Protein bonding 2. Solubility                            6. Chelation 3. Partition coefficient             7. Bioisosterism 4. Hydrogen bonding              8. Stereoisomerism Ionization: It is necessary to know whether a molecule will be ionized at a given pH simply by knowing if the functional groups on the … Read more