PHYSIOCHEMICAL PROPERTIES IN RELATION TO BIOLOGICAL ACTION
The various physiochemical properties affecting the drug action are- 1. Ionization 5. Protein bonding 2. Solubility 6. Chelation 3. Partition coefficient 7. Bioisosterism 4. Hydrogen bonding 8. Stereoisomerism Ionization: It is necessary to know whether a molecule will be ionized at a given pH simply by knowing if the functional groups on the … Read more